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Financial Review
Pfizer Inc. and Subsidiary Companies
24
2015 Financial Report
Revenues—Major Products
The following table provides revenue information for several of our major products:
(MILLIONS OF DOLLARS) Year Ended December 31, % Change
PRODUCT PRIMARY INDICATIONS 2015 2014 2013 15/14 14/13
INNOVATIVE PRODUCTS BUSINESS(a) $ 26,758 $ 24,005 $ 23,602 11 2
GIP(a) $ 13,954 $ 13,861 $ 14,317 1(3)
Lyrica GIP(b) Epilepsy, post-herpetic neuralgia and diabetic peripheral
neuropathy, fibromyalgia and neuropathic pain due to spinal cord
injury
3,655 3,350 2,965 913
Enbrel (Outside the U.S. and Canada) Rheumatoid, juvenile rheumatoid and psoriatic arthritis, plaque
psoriasis and ankylosing spondylitis 3,333 3,850 3,774 (13) 2
Viagra GIP(c) Erectile dysfunction 1,297 1,181 1,180 10 —
BeneFIX Hemophilia 752 856 832 (12) 3
Chantix/Champix An aid to smoking cessation treatment 671 647 648 4—
Genotropin Replacement of human growth hormone 617 723 772 (15) (6)
Refacto AF/Xyntha Hemophilia 533 631 602 (16) 5
Xeljanz Rheumatoid arthritis 523 308 114 70 *
Toviaz Overactive bladder 267 288 236 (7)22
BMP2 Development of bone and cartilage 232 228 209 29
Somavert Acromegaly 218 229 217 (5)6
Rapamune Prevention of organ rejection in kidney transplantation 197 339 350 (42) (3)
Alliance revenue GIP(d), (o) Various 1,254 762 1,878 65 (59)
All other GIP(e) Various 405 469 540 (14) (13)
VOC(a) $ 12,803 $ 10,144 $ 9,285 26 9
Prevnar family(f) Vaccines for prevention of pneumococcal disease 6,245 4,464 3,974 40 12
Sutent Advanced and/or metastatic renal cell carcinoma (mRCC),
refractory gastrointestinal stromal tumors (GIST) and advanced
pancreatic neuroendocrine tumor
1,120 1,174 1,204 (5)(2)
Ibrance Advanced breast cancer 723 ——*—
Xalkori Anaplastic lymphoma kinase positive non-small cell lung cancer 488 438 282 11 55
Inlyta Advanced renal cell carcinoma (RCC) 430 410 319 528
FSME-IMMUN/TicoVac Tick-borne encephalitis vaccine 104 ——*—
All other V/O(e) Various 298 211 164 41 29
Consumer Healthcare Various 3,395 3,446 3,342 (1)3
ESTABLISHED PRODUCTS BUSINESS(g) $ 21,587 $ 25,149 $ 27,619 (14) (9)
Legacy Established Products(h) $ 11,745 $ 13,016 $ 14,089 (10) (8)
Lipitor Reduction of LDL cholesterol 1,860 2,061 2,315 (10) (11)
Premarin family Symptoms of menopause 1,018 1,076 1,092 (5)(1)
Norvasc Hypertension 991 1,112 1,229 (11) (10)
Xalatan/Xalacom Glaucoma and ocular hypertension 399 495 589 (19) (16)
Zoloft Depression and certain anxiety disorders 374 423 469 (12) (10)
Relpax Treats the symptoms of migraine headache 352 382 359 (8)6
EpiPen Epinephrine injection used in treatment of life-threatening allergic
reactions 339 294 273 15 8
Effexor Depression and certain anxiety disorders 288 344 440 (16) (22)
Zithromax/Zmax Bacterial infections 275 311 387 (11) (20)
Xanax/Xanax XR Anxiety disorders 224 253 276 (11) (8)
Cardura Hypertension/Benign prostatic hyperplasia 210 263 296 (20) (11)
Neurontin Seizures 196 210 216 (7)(3)
Diflucan Fungal infections 181 208 238 (13) (13)
Tikosyn Maintenance of normal sinus rhythm, conversion of atrial
fibrillation/flutter 179 141 119 27 19
Depo-Provera Contraceptive 170 201 191 (15) 2
Unasyn Injectable antibacterial 118 96 84 23 14
All other Legacy Established Products(e), (o) Various 4,571 5,145 5,516 (11) (7)
Peri-LOE Products(i) $5,326 $8,855 $ 10,151 (40) (13)
Lyrica GEP(b) Epilepsy, neuropathic pain and generalized anxiety disorder 1,183 1,818 1,629 (35) 12
Zyvox Bacterial infections 883 1,352 1,353 (35) —
Celebrex Arthritis pain and inflammation, acute pain 830 2,699 2,918 (69) (8)
Pristiq Depression 715 737 698 (3)6
Vfend Fungal infections 682 756 775 (10) (2)
Viagra GEP(c) Erectile dysfunction 411 504 701 (18) (28)
Revatio Pulmonary arterial hypertension (PAH) 260 276 307 (6)(10)
All other Peri-LOE Products(e) Various 362 714 1,770 (49) (60)
Sterile Injectable Pharmaceuticals(j) $3,944 $3,277 $3,378 20 (3)
Medrol Inflammation 402 381 398 5(4)
Sulperazon Antibiotic 339 354 309 (4)15
Fragmin Anticoagulant 335 364 359 (8)2
Tygacil Antibiotic 304 323 358 (6)(10)