Merck 2014 Annual Report Download - page 34
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29MAGAZINE → Health for everyone
WORMS OF THE GENUS SCHISTOSOMA,
THE CAUSE OF SCHISTOSOMIASIS,
LIVE IN STAGNANT BODIES OF WATER.
People infected with worm eggs
contaminate freshwater with their
excreta.
Schistosoma eggs
pass from the body into
the water.
Once in the water, miracidia hatch from
the eggs and use the freshwater snail
as an intermediate host . . .
. . . and then grow into cercaria. The cercaria
penetrate human skin, primarily attacking the
bladder and colon via the blood and lymphatic
systems.
Praziquantel is well tolerated, and the
only active ingredient with which all
forms of schistosomiasis can be treated.
TRANSMISSION OF SCHISTOSOMIASIS →
VIA PEOPLE AND INTERMEDIATE HOSTS